A/Prof Sim currently works as lead clinician treating brain cancer patients at The Kinghorn Cancer Centre and Chris O’Brien Lifehouse in Sydney. He is the Clinical Lead and Group Coordinator of the Cooperative Trials Group for Neuro-Oncology (COGNO) and Chair of the COGNO International Clinical Research Subcommittee.
A/Prof Sim’s research focus is the design and operationalisation of investigator-initiated brain cancer trials. As a productive mid-career clinical researcher, he has secured over $11.6 million in peer-reviewed funding, multiple awards (including ASCO Merit Award, NOYCIA Award, CAHON Young Investigator Award), and authored 44 peer-reviewed manuscripts (including Journal of Clinical Oncology, Neuro-Oncology, Clinical Cancer Research) and a book chapter.
Current Projects & Areas of Interest:
Drug development and clinical trials for patients with primary brain cancer
Advancement of clinical trial methodology
Lead of the COGNO-led PICCOG study which will evaluate a novel treatment for patients with relapsed IDH-mutant gliomas